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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Norethindrone and St John's Wort

Research Papers that Mention the Interaction

RESULTS Concomitant use of St John's wort was associated with a significant (P <.05) increase in the oral clearance of norethindrone (8.2 +/-
…St John's wort was associated with a significant (… the oral clearance of norethindrone (8.2 +/- 2.7 L/h to 9.5 +/- 3.4 L/h, P =.042) and a significant …-life of ethinyl estradiol (23.4 +/- 19.5 hours to 12.2 +/- 7.1 hours, P =.023).
Clinical pharmacology and therapeutics  •  2003  |  View Paper