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Last Updated: 3 months ago

Possible Interaction: Norethindrone and Progesterone

Research Papers that Mention the Interaction

Oral administration of norethindrone significantly reduced the cytoplasmic and nuclear receptor concentration for estradiol and progesterone.
Molecular and Cellular Endocrinology  •  1980  |  View Paper
Norethindrone (17beta-hydroxy-19-nor-17alpha-pregn-4-en-20-yn-3-one) and norethindrone acetate (17beta-acetoxy-19-nor-…-pregn-4-en-20-yn-3-one) interfered to a varying degree, by competitive inhibition, with the binding of progesterone and oestradiol to respective cytoplasmic … in the human uterus.
The Biochemical journal  •  1978  |  View Paper
Norethisterone and methyloestrenolone were the most effective inhibitors of progesterone formation : when incubated in an equimolar concentration (35 mumol/1) with pregnenolone (50 microgram) the progesterone formation was reduced to 60.0-62.7% and 29.1-34.0% respectively of that of the respective control experiments.
Journal of reproduction and fertility  •  1977  |  View Paper
The strongest inhibition on progesterone formation was induced by Δ 4 -3-keto-19-nortestosterone derivatives, norethisterone and methylestrenolone.
European journal of obstetrics, gynecology, and reproductive biology  •  1976  |  View Paper
.5 mg of norethindrone depressed the levels of LH progesterone and pregnanediol and the decomposition of estrogens was increased.
mg of norethindrone depressed the levels of LH progesterone and pregnanediol and the decomposition of estrogens was increased.
Lakartidningen  •  1970  |  View Paper
From these results we conclude that the introduction of the 18-methyl in norethisterone (levonorgestel) increases both the binding to the progesterone and androgen receptors.(ABSTRACT TRUNCATED AT 250 WORDS)
Contraception  •  1988  |  View Paper
500 mg progesterone suppositories delayed menses for up to 7 days while 30 mg norethisterone (17alpha-ethinyl-19-nortestosterone) effectively inhibite d menses for as long as 6 months.
Annals of the New York Academy of Sciences  •  1958  |  View Paper
NET is a compound with five- to eight-fold weaker PR binding and transactivation activities than the reference compound Org 2058 (100%) and two-fold stronger than progesterone.
The Journal of Steroid Biochemistry and Molecular Biology  •  2000  |  View Paper
During treatment with norethindrone, progesterone levels decreased.
Contraception  •  1974  |  View Paper
In contrast, progesterone alone had no effect, in young intact or adult castrated males, but norethindrone did stimulate mammary growth.
Physiological research  •  2001  |  View Paper
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