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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Norepinephrine
supplement:
Trypsin
Research Papers that Mention the Interaction
“In human fat cells, on the contrary, trypsin failed to modify the antilipolytic effect of insulin, but markedly potentiated the lipolytic response to epinephrine, norepinephrine and isoproterenol.”
Influence of trypsin on lipolysis in human fat cells. Comparison with rat adipocytes.“Treatment of endogenous lipid droplets with phospholipase C, but not phospholipase D, trypsin , chymotrypsin, or neuraminidase, inhibited the propranolol-sensitive binding of norepinephrine to the droplets.”
Propranolol-sensitive and phenoxybenzamine-insensitive binding of norepinephrine to endogenous lipid droplets from rat adipocytes.“ Trypsin treatment caused partial loss of norepinephrine binding activity , while cyclic AMP binding activity was completely lost.”
“The Na+ and energy dependent uptake of norepinephrine into cortical rat brain homogenates or purified nerve ending particles (NEP) is reduced by prior trypsin treatment.”
“Extraction of these membranes by deoxycholate as well as treatment with phospholipase C (EC 3.1.4.3) or trypsin (EC 3.4.4.4) markedly reduced the adenylate cyclase activity in the absence or presence of NaF and norepinephrine.”
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