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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Norepinephrine
supplement:
S-Adenosylmethionine
Research Papers that Mention the Interaction
“Exaggerated standing NE is found in depressed patients; SAMe may reduce this abnormal response, providing a clue for its mechanism of action in depression.”
“Standing HR and plasma NE were reduced following chronic SAMe.”
Effects of S-adenosyl-methionine on plasma norepinephrine, blood pressure, and heart rate in healthy volunteers“ SAM may indirectly affect NA biosynthesis and metabolism.”
“The noradrenaline NA ) concentration increased in the hippocampus and frontal cortex and decreased in the olfactory bulbs between 1 and 2 h after the SAM injection.”
Acute effects of S-adenosyl-L-methionine on catecholaminergic central function.“ Noradrenaline addition increases (S-adenosyl-L-methionine)-methylation of chloroform extractable products in the rat brain synaptosomal preparation.”
“ S-adenosylmethionine (0,1 mg/kg/ip) decreases in vivo, norepinephrine (NE) synthesis and does not affect 5-hydroxytryptamine (5 HT) synthesis in the Rat brain.”
“Incubation of rat and bovine epiphysis with norepinephrine (10(-5)-10(-6) M) in the presence of S-adenosylmethionine and guanidineacetic acid resulted in the increase of the creatine synthesis rate.”
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