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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Norepinephrine and Polyphenols

Research Papers that Mention the Interaction

TPs administration could effectively reverse the alterations in the concentrations of 5-HT and NE , elevate the activities of SOD and CAT as well as the level of GSH, reduce the MDA level and inhibit lipid peroxidation.
Pharmacology Biochemistry and Behavior  •  2013  |  View Paper
That catechin-polyphenols are known to be capable of inhibiting catechol-O-methyltransferase (the enzyme that degrades norepinephrine ) is a possible explanation for why the green tea extract is effective in stimulating thermogenesis by epigallocatechin gallate to augment and prolong sympathetic stimulation of thermogenesis.
Journal of medicinal food  •  2006  |  View Paper
catechin-polyphenols are known to be … (the enzyme that degrades NA ), and caffeine to inhibit trancellular phosphodiesterases (enzymes that break down NA-induced cAMP), it is proposed that the green … and caffeine, is effective in stimulating thermogenesis by relieving inhibition at different control points along the NA–cAMP axis.
International Journal of Obesity  •  2000  |  View Paper
A series of polyphenols have been found to reduce methylation of epinephrine and norepinephrine by O-methyl transferase in vitro, probably by acting as competitive substrates.
The Journal of pharmacology and experimental therapeutics  •  1960  |  View Paper