supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Norepinephrine
supplement:
Methylselenocysteine
Research Papers that Mention the Interaction
“Thus, NE had a protective effect on MSC apoptosis induced by high glucose, possibly via the AKT/BCL‐2 pathway.”
Norepinephrine protects against apoptosis of mesenchymal stem cells induced by high glucose“An in vitro Transwell assay … here used to demonstrate that NE can inhibit stroma-derived factor-1 (SDF-1)-induced MSC migration and expression of the migration-related gene matrix metalloproteinase-2 (MMP-2) and downregulate that of the anti-migration gene tissue inhibitor of metalloproteinase-3 (TIMP-3).”
“An in vitro osteogenic … used to show that NE can inhibit … of MSC bone nodules and expression of the osteogenic marker genes alkaline phosphatase (ALP), osteocalcin (OCN), and runt-related transcription …-2 (RUNX2), but knockdown of adrb3 by siRNA can abolish such inhibition of the osteogenic differentiation of MSCs.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback