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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Norepinephrine
supplement:
Magnesium Cation
Research Papers that Mention the Interaction
“ Mg++ , DL-2-amino-5-phosphonopentanoic acid and MK-801 (D-5-methyl-10,11,dihydro-5H-dibenzo[a,d] cyclohepten-5-10-imine maleate), but not 6-cyano-7-nitroquinoxaline-2,3-dione, inhibited the L-glutamic acid-evoked release of NE.”
Release of endogenous norepinephrine from rat hypothalamus by stimulation of N-methyl-D-aspartic acid receptors.“The results indicate that in the pulmonary artery, Mg++ alters the sensitivity to histamine but not to norepinephrine, and may differentially inhibit bound Ca++ release by norepinephrine and histamine.”
“Phenytoin and the Mg2+ ion were found to have a marked inhibitor effect by increasing the threshold norepinephrine concentration and decreasing the maximal rate of depolarization of SR.”
“4 Magnesium ions (1.2, 3.6, 12.0 and 24.0 mm) inhibited the contractile responses induced by low concentrations of noradrenaline (2 × 108m) and KCl (2 × 10 −2m).”
“The membrane effects and the inotropic effect of norepinephrine were inhibited by the addition of Mg++ to Ca++-free media.”
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