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“Racemic tramadol and its (+)- and (-)-enantiomers (all at 5 mumol litre-1) significantly increased stimulated norepinephrine efflux (P < 0.01) by mean 66 (SEM 10)%, 57 (7)% and 64 (13)%, respectively.”
British journal of anaesthesia • 1999 | View Paper
“This suggests that (-)-amosulalol but not (+)-amosulalol, at 10(-6) M is an alpha 2-adrenoceptor antagonist and that (+)- but not (-)-amosulalol, at 10(-5) M, inhibits the neuronal uptake process for noradrenaline.”
Journal of cardiovascular pharmacology • 1987 | View Paper
“(+)-TCP, pargyline and (-)-deprenyl potentiate the effect of tyramine, while that of noradrenaline is potentiated by (+)- as well as (-)-TCP and (-)-deprenyl.”