supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Norepinephrine
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Indeed, NA enhances intracellular Ca2+by increasing its influx through voltage-dependent channels, mobilising it from intracellular stores and favouring its inward transport by Na+/Ca2+ exchange.”
Therapeutic potential of H3-receptor agonists in myocardial infarction“There is evidence of altered norepinephrine levels in the hypothalamus as a consequence of manipulations of dietary calcium as well as changes in central sympathetic nervous system outflow.”
“Insulin, angiotensin II, arginine vasopressin, and norepinephrine significantly increased calcium (to 115±7, 183±20, 184±15, and 168±12 nmol/L, respectively, from basal calcium of 90±10 nmol/L).”
“ Calcium loading both attenuated the development of hypertension and reduced the pressor response to norepinephrine.”
“ Noradrenaline (fl) and calcitonin gene-related peptide (Ryu et al., 1988) enhance neuronal Ca 2 + currents.”
“Several neurotransmitters noradrenaline , GABA, 5 HT and dopamine) all inhibit Ca 2÷ currents recorded from chick sensory neurones, this shows convergence of receptor mechanisms onto a single effector, the Ca 2+ channel.”
“It also influenced intracellular calcium such that consistently higher total levels were observed in response to bradykinin, angiotensin II and norepinephrine , as compared to similarly treated uninfected cells.”
“Nifedipine and calcium free " solution decreased the noradrenaline induced contraction but did not influence the relaxant response to electrical stimulation.”
“In depolarized muscle, however, norepinephrine increased the cellular low affinity bound Ca.”
“The presynaptic muscarine receptor of adrenergic nerve terminals probably restricts the influx of calcium ions that triggers the release of NE.”
“Stimulation of the muscle strips with norephinephrine or high external potassium significantly (P<0.05) increased the calcium uptake over the control values at 30 and 100 min, whereas 45Ca efflux was virtually not affected.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback