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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitrous Oxide
supplement:
Levomefolate
Research Papers that Mention the Interaction
“In the rats exposed to nitrous oxide, cytosolic 5-methyltetrahydrofolate concentrations were significantly greater (59% of total folates) and tetrahydrofolate concentrations were significantly lower (32%) than in controls; however, total cytosolic folate levels were unaffected by nitrous oxide exposure.”
Compartmentation of folate metabolism in rat pancreas: nitrous oxide inactivation of methionine synthase leads to accumulation of 5-methyltetrahydrofolate in cytosol.
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