supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Nitrous Acid
supplement:
Vitamin C
Research Papers that Mention the Interaction
“In addition, nitrous acid can react with ascorbic acid and phenolics producing NO and with H(2)O(2) producing ONOOH.”
Detection of nitric oxide and its derivatives in human mixed saliva and acidified saliva.“It has been hypothesized that dietary nitrate and nitrite are converted in the stomach to nitrous acid, which reacts … amines and amides to form nitrosamines and nitrosamides, compounds frequently demonstrated to be carcinogenic in animals, and that vitamins C and E inhibit N-… formation by chemically reducing nitrous acid.”
“In all instances, the reactions of the drugs with nitrous acid were inhibited and, in most cases, completely prevented by the presence of ascorbic acid (125 mg).”
“If reductones such as ascorbic acid are present, they may react much faster with nitrous acid than amines and therefore effectively scavenge the nitrosating agent.”
Catalysis and inhibition of N-nitrosation reactions.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback