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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitroprusside
supplement:
Progesterone
Research Papers that Mention the Interaction
“The arrest by SNP in the formation of syncytial cells was further evidenced by the low secretion profile of hCG and progesterone.”
Localization of Nitric Oxide Synthase in Human Trophoblast Cells: Role of Nitric Oxide in Trophoblast Proliferation and Differentiation“Donator of nitrogen oxide (0.1 mM sodium nitroprusside ) in the presence of progesterone substantially promoted the level of cAMP in cells at the protracted action (17 +/- 3 pmol cAMP/mg protein).”
[Active nitrogen and oxygen metabolites change cAMP level in the uterus myocytes treated by progesterone].“ NP caused a two- to fivefold decrease in release of progesterone from CL of both ages, and this inhibitory effect on steroidogenesis was reversed by l-NAME.”
“Moreover, the conversion of [3H]cholesterol to [3H]pregnenolone and the production of pregnenolone or progesterone (assessed by RIA) were significantly decreased by SNP.”
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