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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitroprusside
supplement:
Kaempferol
Research Papers that Mention the Interaction
“ KF suppressed the release of nitric oxide (NO) and prostaglandin E2 (PGE2), downregulated the cellular adhesion of U937 cells to fibronectin (FN), neutralized the … expression levels of inflammatory genes encoding inducible NO synthase (iNOS), TNF-α, and cyclooxygenase- (COX-) 2 in lipopolysaccharide- (LPS-) and sodium nitroprusside- ( SNP- ) treated … macrophages.”
The Dietary Flavonoid Kaempferol Mediates Anti-Inflammatory Responses via the Src, Syk, IRAK1, and IRAK4 Molecular Targets“Apigenin and luteolin , but not (-)-α-bisabolol, enhanced the relaxation to the nitric oxide donor sodium nitroprusside , indicating that apigenin and luteolin may act to regulate cyclic GMP levels.”
Distinct mechanisms of relaxation to bioactive components from chamomile species in porcine isolated blood vessels.“In endothelium-disrupt rings, kaempferol (10 μM) also enhanced the relaxation caused by isoproterenol, sodium nitroprusside , levcromakalim and nifedipine.”
“However, luteolin (10-20 microM) produced parallel and leftward shifts of the concentration-response curve of forskolin or nitroprusside.”
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