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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitroprusside
supplement:
Epigallocatechin Gallate
Research Papers that Mention the Interaction
“ EGCG ameliorated caspase-9 and -3 activities and cytochrome c release increased by SNP.”
“ EGCG was administered for 1 hr before the SNP treatment, resulting in increased cell viability and reactive oxygen species (ROS) production inhibition.”
Epigallocatechin gallate protects against nitric oxide-induced apoptosis via scavenging ROS and modulating the Bcl-2 family in human dental pulp cells.“ EGCG abrogated the activation of caspase-9, caspase-8 and caspase-3 induced by SNP.”
“ EGCG attenuated the production of reactive oxygen species (ROS) by SNP , and ameliorated the SNP-induced Bax to Bcl-2 expression ratio leading to apoptosis.”
“ EGCG inhibited the cytotoxicity and apoptotic morphogenic changes induced by SNP.”
Epigallocatechin gallate inhibits nitric oxide-induced apoptosis in rat PC12 cells“Importantly, when EGCG was co-injected, the detrimental effects to the retina caused by SNP were significantly blunted.”
“Initial in vitro studies on brain membranes showed that EGCG was approximately 10 times more potent than trolox (vitamin E analogue) at attenuating lipid peroxidation caused by the nitric oxide donor, sodium nitroprusside (SNP).”
“The conclusion reached from this study is that EGCG is a powerful antioxidant and when injected into the eye with SNP attenuated the detrimental influence of SNP to retinal photoreceptors.”
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