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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitroprusside
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Alone of the NO donors, low concentrations of L-arginine produced a mild inhibition of histamine release induced by anti-IgE, compound 48/80 and A23187, but not other ligands, while sodium nitroprusside dose-dependently inhibited (by a maximum of ca.”
Role of nitric oxide in histamine release from human basophils and rat peritoneal mast cells.“When added after thrombin, PGI and SNP accelerate the BSA-activated decay of [ Ca].”
“This characteristic distinguishes them from other drugs such as sodium nitroprusside , papaverine, hydralazine and diazoxide which interfere with the availability of calcium ions for their physiological functions by acting at sites other than the 'calcium channels'.”
“Our results showed that sodium nitroprusside inhibited sperm motility and motion kinematics in a dose‐dependent manner by significantly enhancing intracellular iron and reactive oxygen species (ROS), and decreasing Ca2+ , and adenosine triphosphate levels in spermatozoa.”
“This characteristic distinguishes them from other drugs such as sodium nitroprusside , papaverine, hydralazine and diazoxide which interfere with the availability of calcium ions for their physiological functions by acting at sites other than the ‘calcium channels’.”
“The Ca 2 + ] i peak was reduced by 66 - 4% after preincubation in 100 w mol/l sodium nitroprusside , and by 90 - 2% after preincubation in 10 mu mol/l prostaglandin E 1 .”
“Both are strongly reduced if Ca2+ addition is preceded by SNP or PGI2.”
“ Nitroprusside was also able to inhibit intracellular calcium translocation, as studied with the Quin 2 technique, induced by PAF and arachidonic acid.”
“The other, which can be inhibited by sodium nitroprusside , involves the entry of calcium through agonist-controlled channels and probably its mobilization from within the cell as well.”
“In vitro, on the contrary, a concentration-dependent decrease in Ca2+ -uptake caused by NG as well as SNP is observed together with simultaneous decrease of deltapsim and concentration-dependent release of Ca2+ from mitochondria via Ca2+-uniporter as the result of partial depolarisation of mitochondrial inner membrane.”
[Effect of nitric oxide donors on Ca2+-uptake in the rat heart and liver mitochondria].
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