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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Nitroprusside
Research Papers that Mention the Interaction
“There is evidence to indicate, however, that SNP inhibits hypoxic vasoconstriction and may increase intrapulmonary shunt fraction ( Qs/QT ) (1,2), responses which could be particularly deleterious in patients with limited cardiopulmonary reserve.”
Differential effect of prostaglandin E1 and sodium nitroprusside on intrapulmonary shunt fraction in a cardiac transplantation patient.“The authors investigated why intrapulmonary shunt QS/QT ) increases with sodium nitroprusside (SNP) in canine oleic acid pulmonary edema.”
Direct effects of nitroprusside do not alter gas exchange in canine oleic acid edema.“The decrease in PVR in the atelectatic lung suggests that SNP decreases PaO2 and increases Qs/Qt by reversing the hypoxic pulmonary vasoconstriction.”
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