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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitroprusside
supplement:
Alpha-Ketoglutarate
Research Papers that Mention the Interaction
“Based on the observed antioxidant activity of AKG, it may be suggested that the antioxidant mode of AKG action (apart from its cyanide-binding capability) may be used to prevent the toxic effects of SNP and improve general physiological state of D. melanogaster and other animals and humans.”
“Food supplementation with 10mM AKG alleviated toxic effects of 1mM SNP added to food and improved fly development.”
Alpha-ketoglutarate attenuates toxic effects of sodium nitroprusside and hydrogen peroxide in Drosophila melanogaster.“These results suggest that the combined administration of AKG and STS, by preventing the increase in blood cyanide levels induced by SNP , may afford protection against the toxic effects of SNP.”
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