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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitroglycerin
supplement:
Melatonin
Research Papers that Mention the Interaction
“Addition of melatonin (10−9–10−7 M) to the organ chamber during the 90‐min incubation period with nitroglycerin partially inhibited nitrate tolerance in coronary arteries with intact endothelium; however, melatonin had no effect on nitrate tolerance in coronary arteries without endothelium.”
Melatonin inhibits nitrate tolerance in isolated coronary arteries“Pretreatment with methylene blue (10(-5) M) or nitroglycerin (3 x 10(-8) M) inhibited or potentiated, respectively, the relaxing action of melatonin.”
“Pretreatment with melatonin (10(-3) M) or M&B 22.948 (10(-3) M) potentiated the relaxing effect of nitroglycerin (10(-9)-10(-5) M) on the contraction induced by PGF2 alpha (4 x 10(-6) M).”
“In the absence of endothelium, nitroglycerin and melatonin potentiated the relaxation by melatonin and nitroglycerin, respectively.”
“ Melatonin potentiated the nitroglycerin relaxation.”
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