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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitroglycerin
supplement:
Ebselen
Research Papers that Mention the Interaction
“Treatment of …/ml) or ebselen (1.5x10(-5) M), a … 90-min exposure period to nitroglycerin resulted in a further rightward shift in the nitroglycerin concentration-response curve in tolerant rings (-logEC50=5.….98+/-0.1; catalase and ebselen respectively), without altering the response to nitroglycerin in control rings.”
Role of endogenous hydrogen peroxide in the development of nitrate tolerance.“In vitro incubation of tolerant rings with ebselen and uric acid markedly increased the depressed P-VASP levels and improved NTG sensitivity of the tolerant vasculature.”
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