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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Nitroglycerin and Ascorbate

supplement:

Ascorbate

Research Papers that Mention the Interaction

Conclusions—Three days of continuous transdermal administration of NTG was accompanied by increased platelet NO and O2·− production and NADH oxidase activity that was suppressed by coadministration of oral ascorbate.
Circulation  •  2002  |  View Paper
Co-administration of ascorbate with NTG resulted in a significant decrease in 8-epi PGF(2alpha) production, from 38.8 (95% CI 24.9 to 52.7) to 19.0 (95% CI 13.5 to 24.5) pg/mg protein (p < 0.05).
Journal of the American College of Cardiology  •  2002  |  View Paper