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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitroglycerin
supplement:
3-Nitrotyrosine
Research Papers that Mention the Interaction
“ Nitroglycerin infusion markedly reduced protein nitrotyrosine and tumor necrosis factor alpha levels in both groups.”
Cardiopulmonary bypass exacerbates oxidative stress but does not increase proinflammatory cytokine release in patients with diabetes compared with patients without diabetes: regulatory effects of exogenous nitric oxide.“Compared with the vehicle group, formation of nitrotyrosine , a footprint for peroxynitrite (ONOO−) production, was markedly increased in the hearts treated with medium-dose or high-dose NTG.”
Glutathione Reverses Peroxynitrite-mediated Deleterious Effects of Nitroglycerin on Ischemic Rat Hearts“ Glyceroltrinitrate administration augmented urinary nitrotyrosine from 56 ± 24 (basal) to 186 ± 32 μg/day (glyceroltrinitrate tolerance).”
Urinary Nitrotyrosine Content as a Marker of Peroxynitrite-induced Tolerance to Organic Nitrates
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