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Last Updated: 3 years ago

Possible Interaction: Nitrofurantoin and Selenium

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drug:

Nitrofurantoin

supplement:

Selenium

Research Papers that Mention the Interaction

“Dietary PZ51 (1280 ppm) or selenium (0.1 ppm) alone or in combination decreased the acute lethalities of nitrofurantoin or paraquat in vitamin E-adequate chicks.”

Synthetic seleno-organic compound with glutathione peroxidase-like activity in the chick.

Biochemical pharmacology • 1986 | View Paper

“The … of Se (0.10 ppm as Na2SeO3) alone, but not E (100 IU/kg diet as dl-alpha-tocopheryl acetate) reduced the toxicity of nitrofurantoin , so that the LD50 for the chicks given Se alone was the same as the LD50 for the E- and Se-fed chicks.”

Effect of selenium and vitamin E deficiency on nitrofurantoin toxicity in the chick.

The Journal of nutrition • 1982 | View Paper

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