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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitric Oxide
supplement:
Valine
Research Papers that Mention the Interaction
“Addition of L-valine , as an arginase inhibitor, leads to a 25% increase in NO formation and an 80-90% decrease in arginase activity.”
In hepatocytes the regulation of NOS-2 activity at physiological L-arginine levels suggests a close link to the urea cycle.“In both control and L/T bPAEC, treatment with L-Val decreased urea production and increased NO production.”
“Finally, the calculations also indicate that a conserved active site valine plays a role in reducing the rate of NO reduction in CcO.”
Mechanisms for enzymatic reduction of nitric oxide to nitrous oxide - A comparison between nitric oxide reductase and cytochrome c oxidase.“ Valine and isoleucine also reduced NO production by 29.65 and 42.95%, respectively.”
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