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Last Updated: 2 years ago

Possible Interaction: Nitric Oxide and Sulforaphane

supplement:

Sulforaphane

Research Papers that Mention the Interaction

Results: Our results showed that the combination of SFN and APAP exhibited an inhibitory effect on inflammatory markers such as NO , iNOS, COX-2, and IL-1β, and this effect was more pronounced than the compound was used alone.
Immunopharmacology and immunotoxicology  •  2019  |  View Paper
SFN significantly increased hepatic GSH level as well as catalase and glutathione-S-transferase activities while counteracted the elevation in hepatic oxidative stress markers; MDA, NO and protein carbonyl in aged rats.
European journal of pharmacology  •  2019  |  View Paper
In addition, SF significantly decreases the NO in a concentration-dependent manner.
Inflammation Research  •  2009  |  View Paper
DMF and SP attenuated the LPS-induced production and release of TNFalpha, IL-1beta, IL-6 and NO.
Journal of Neuroimmunology  •  2005  |  View Paper
SFN was able to prevent the expression of NO and cytokines through regulating inflammatory enzyme iNOS and activation of Nrf2/HO-1 signal transduction pathway.
Antioxidants  •  2019  |  View Paper
We … that sulforaphane significantly attenuated the blood-brain barrier (BBB) disruption; decreased the levels of pro-… cytokines tumor necrosis factor (TNF)-α and interleukin (IL)-1β; reduced the nitric oxide (NO) levels and inducible nitric oxide synthase (iNOS) activity; inhibited the expression of iNOS and cyclooxygenase-2 (COX-2).
International journal of clinical and experimental medicine  •  2015  |  View Paper
ResultsWe report that combination of PEITC + SFN or CUR + SFN has a synergistic effect in down-regulating inflammation markers like TNF, IL-1, NO , PGE2.
Pharmaceutical Research  •  2008  |  View Paper