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“Results: Our results showed that the combination of SFN and APAP exhibited an inhibitory effect on inflammatory markers such as NO , iNOS, COX-2, and IL-1β, and this effect was more pronounced than the compound was used alone.”
Immunopharmacology and immunotoxicology • 2019 | View Paper
“ SFN significantly increased hepatic GSH level as well as catalase and glutathione-S-transferase activities while counteracted the elevation in hepatic oxidative stress markers; MDA, NO and protein carbonyl in aged rats.”
“ SFN was able to prevent the expression of NO and cytokines through regulating inflammatory enzyme iNOS and activation of Nrf2/HO-1 signal transduction pathway.”
“We … that sulforaphane significantly attenuated the blood-brain barrier (BBB) disruption; decreased the levels of pro-… cytokines tumor necrosis factor (TNF)-α and interleukin (IL)-1β; reduced the nitric oxide (NO) levels and inducible nitric oxide synthase (iNOS) activity; inhibited the expression of iNOS and cyclooxygenase-2 (COX-2).”
International journal of clinical and experimental medicine • 2015 | View Paper
“ResultsWe report that combination of PEITC + SFN or CUR + SFN has a synergistic effect in down-regulating inflammation markers like TNF, IL-1, NO , PGE2.”