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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Nitric Oxide
supplement:
Scutellaria Baicalensis
Research Papers that Mention the Interaction
“Among them, SB-HW (80 μg/mL)/CM-E (120 μg/mL) or SB-HW (40 μg/mL)/CM-E (160 μg/mL) significantly inhibited LPS-stimulated NO and IL-6 levels in RAW 264.7 cells.”
Anti-inflammatory action of herbal medicine comprised of Scutellaria baicalensis and Chrysanthemum morifolium“The results showed that SR exhibited radical-scavenging activities in a dose-dependent manner; in addition, SR attenuated the Cu2+-induced oxidation of LDL as well as significantly inhibited nitric oxide (NO) production and inducible NO synthase (iNOS) expression in LPS-induced RAW264.7 cells.”
“NF-κB p65 may be involved in the pathogenesis of UC, and huangqin tang can inhibit the relative activity of NF-κB p65, and decrease the expression levels of NO , IL-6, TNF-α and PGE2.”
[Effect of huangqin tang on the regulatory NF-κB p65 signal pathway in rats with ulcerative colitis].“RESULTS … SR si gnificantly inhibited … NO, i nterleukin (IL)-3, IL-6, IL-10, IL-12p40, IL-17, interferon-inducible protein (IP)-10, keratinocyte-derived chemokine (KC), and vascular endothelial … (VEGF) in LPS-induced RAW 264.7 cells at the concentrations of 25, 50, 100, 200 microg/ml (p<0.05).”
“Furthermore, reactive oxygen species and nitric oxide production were significantly attenuated by EESB treatment.”
“ SBR (46.1 ± 0.9 %) and MOB (48.9 ± 1.0 %) extracts effectively inhibited NO production, and dose-dependently reduced the expression of TNF-α, iNOS, NF-κB, COX2, and IL-6.”
Pharmaceutical Advantages of GenoTX-407, A Combination of Extracts from Scutellaria baicalensis Root and Magnolia officinalis Bark“Oriental herbs such as Angelica tenuissima, Angelica dahurica, and Scutellaria baicalensis reduced the production of nitric oxide and the expression of COX-2.”
“A study by M.-H. So … that the water extracts of Scutellariae radix and Liriopis … production of nitric oxide , interleukin-6, macrophage inflammatory protein-1α, macrophage inflammatory protein-1s, macrophage inflammatory protein-2, and … well as the increase of the intracellular free calcium in mouse macrophages induced by lipopolysaccharide.”
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