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“Moreover, both Sm and silymarin treatment inhibited the elevation of hepatic inducible nitric oxide (iNOS) protein content and nitrite concentration in liver homogenate 24 h after CCl(4) intoxication.”
Hepatobiliary & pancreatic diseases international : HBPD INT • 2003 | View Paper
“These results suggest that the traditional use of S. miltiorrhiza as an anti-inflammatory herbal medicine may be explained, in part, by the inhibition of NO , IL-1beta, IL-6 and TNF-alpha production, and expression of iNOS.”
“In order to clarify the mechanism responsible, we investigated whether Salviae Miltiorrhizae Radix extract and several of its related compounds, including caffeic acid and its polymers which were isolated by our research group, can regulate the generation and release of NO.”