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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitric Oxide
supplement:
S-Allylcysteine
Research Papers that Mention the Interaction
“These data demonstrate that garlic extract and SAC , due to their antioxidant activity, differentially regulate NO production by inhibiting iNOS expression in macrophages while increasing NO in endothelial cells.”
Differential regulation of NO availability from macrophages and endothelial cells by the garlic component S-allyl cysteine.“Further more, SAC treatment increased NO and cGMP level of TEV-1 cells and explants in a dose-dependent manner even at non-oxidative stress status (p < 0.05).”
“However, when the TEV-1 cells were cultured in the presence of NOS inhibitor (L-NAME) and NO donor (SNP), additional SAC treatment still significantly increased the NO level in comparison with SAC non-treated group (p < 0.05).”
“In conclusion, SAC ameliorates LPS-induced indicators of liver damage and suppresses the discharge of NO and MPO in lung tissue via its antioxidant properties.”
“MPO activity and NO levels were decreased by SAC application in sepsis + SAC group compared with sepsis group.”
Effects of S-allyl cysteine on lung and liver tissue in a rat model of lipopolysaccharide-induced sepsis
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