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Last Updated: 5 years ago

Possible Interaction: Nitric Oxide and Quercetin

supplement:

Quercetin

Research Papers that Mention the Interaction

“In addition, 1 μg/ml (+)-catechin significantly increased fibroblast migration by 2.4-fold compared to that in the control after 24 h. Regarding anti-inflammatory properties, kaempferol (7) and quercetin (6) decreased (p < 0.005) NO production, with IC50 values of 46.6 and 56.2 μM, respectively.”
PloS one  •  2020  |  View Paper
“We also observed that the expression of oxidative stress markers, such as lipid peroxide (LPO), nitric oxide (NO), superoxide dismutase (SOD), glucose-6-phosphate (G6PD), and glutathione (GSH), could be reduced by quercetin , suggesting that the anti-inflammatory function of quercetin comes from its antioxidant effect.”
Journal of immunology research  •  2020  |  View Paper
“It was identified that quercetin and galangin markedly reduced the production of nitric oxide (NO), inducible NO synthase and interleukin-6, and the nuclear translocation of nuclear factor-κB (NF-κB).”
International journal of molecular medicine  •  2018  |  View Paper
“Finally, HPLC analysis clearly demonstrated that quercetin is a major active component with suppressing activity on the release of inflammatory mediators ( NO and PGE2), and the enzyme activities of Src, Syk, and IRAK-1.”
Journal of ethnopharmacology  •  2014  |  View Paper
“Here, we demonstrate that catechin and quercetin have the potential to down-regulate the initial signalling molecule NF-κB which may further inhibit the downstream cascade including TNF-α and NO.”
Innate immunity  •  2012  |  View Paper
“Based on HPLC analysis, quercetin , which inhibits NO and PGE(2) activities, was found as one of the active ingredients in Ph-ME.”
Journal of ethnopharmacology  •  2012  |  View Paper
“ Quercetin enhanced nitric oxide ( NO ) production, which was abolished by an eNOS inhibitor, L-NAME or H89.”
Pharmacology  •  2012  |  View Paper
“Kaempferol and quercetin showed significant inhibitory effects on NO production in response to lipopolysaccharide treatment in macrophage cells in which the PPARgamma was overexpressed; rosiglitazone was less potent than kaempferol and quercetin.”
Life sciences  •  2008  |  View Paper
“In addition to microbicidal activity, quercetin induced dose-dependent decreases in the levels of TNF-α and nitric oxide produced by activated human macrophages.”
Antimicrobial Agents and Chemotherapy  •  2004  |  View Paper
“OTA‐induced NO , TNF‐α, IL‐6, and IL‐8 were significantly reduced in the quercetin pretreated samples indicating its anti‐inflammatory role.”
Environmental toxicology  •  2016  |  View Paper
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