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Last Updated: 2 years ago
drug:
Nitric Oxide
supplement:
Quercetin
Research Papers that Mention the Interaction
“In addition, 1 μg/ml (+)-catechin significantly increased fibroblast migration by 2.4-fold compared to that in the control after 24 h. Regarding anti-inflammatory properties, kaempferol (7) and quercetin (6) decreased (p < 0.005) NO production, with IC50 values of 46.6 and 56.2 μM, respectively.”
Anti-inflammatory, wound healing and antioxidant potential of compounds from Dioscorea bulbifera L. bulbils“We also observed that the expression of oxidative stress markers, such as lipid peroxide (LPO), nitric oxide (NO), superoxide dismutase (SOD), glucose-6-phosphate (G6PD), and glutathione (GSH), could be reduced by quercetin , suggesting that the anti-inflammatory function of quercetin comes from its antioxidant effect.”
“It was identified that quercetin and galangin markedly reduced the production of nitric oxide (NO), inducible NO synthase and interleukin-6, and the nuclear translocation of nuclear factor-κB (NF-κB).”
“Finally, HPLC analysis clearly demonstrated that quercetin is a major active component with suppressing activity on the release of inflammatory mediators ( NO and PGE2), and the enzyme activities of Src, Syk, and IRAK-1.”
“Here, we demonstrate that catechin and quercetin have the potential to down-regulate the initial signalling molecule NF-κB which may further inhibit the downstream cascade including TNF-α and NO.”
“Based on HPLC analysis, quercetin , which inhibits NO and PGE(2) activities, was found as one of the active ingredients in Ph-ME.”
“ Quercetin enhanced nitric oxide ( NO ) production, which was abolished by an eNOS inhibitor, L-NAME or H89.”
“Kaempferol and quercetin showed significant inhibitory effects on NO production in response to lipopolysaccharide treatment in macrophage cells in which the PPARgamma was overexpressed; rosiglitazone was less potent than kaempferol and quercetin.”
“In addition to microbicidal activity, quercetin induced dose-dependent decreases in the levels of TNF-α and nitric oxide produced by activated human macrophages.”
“OTA‐induced NO , TNF‐α, IL‐6, and IL‐8 were significantly reduced in the quercetin pretreated samples indicating its anti‐inflammatory role.”
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