Possible Interaction: Nitric Oxide and Potassium

“During muscle contraction, we demonstrate redundancies between potassium and nitric oxide as well as between potassium and adenosine.”

“We show that potassium can inhibit vasodilatations induced by adenosine and nitric oxide , and also that adenosine and nitric oxide can interact in a way that changes over time.”

“These findings reveal a previously unidentified pivotal role of NO in modulating the homeostasis of vitamin B6 and potassium nutrition in plants, and shed light on the mechanism of NO in plant acclimation to environmental changes.”

“In SSM … of NO donors (48 nmol to 1 mmol) increased LY uptake (0.5 mmol SNAP 38.4 ± 7.…; 1 mmol GSNO 28.1 ± 7.4 %, p < 0.05) and the refilling rate of potassium (SNAP 227.9 ± 30.1 %, p < 0.….6 ± 28.1 %, p < 0.05).”

“Because it has been reported that NO activates different types of potassium (K(+)) channels in the brain, this study investigated the involvement of K(+) channels in the antidepressant-like effect of venlafaxine in the mouse FST.”

“Since it has been reported that NO can activate different types of potassium (K(+)) channels in several tissues, the present study investigated the possibility of synergistic interactions between different types of K(+) channel inhibitors and tramadol in the mouse FST.”

“In some MCCs, NO blocked an additional potassium current that resulted in current reversal near the potassium equilibrium potential in current-voltage plots.”

“Therefore, NO inhibits cell proliferation irreversibly via a potassium channel‐dependent but guanylate cyclase‐independent pathway in murine mastocytoma cells.”

“ Potassium chloride‐evoked GABA, noradrenaline and nitric oxide release in the olfactory bulb was also significantly enhanced during pro‐oestrus/oestrus.”

“ NO decreases the V max of the enzyme without altering the K m for ATP.”