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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitric Oxide
supplement:
Phosphatidylinositol 4,5-Diphosphate
Research Papers that Mention the Interaction
“Here, we show 1) that the long-lasting response of GnRH neurons to kisspeptin depends on the degradation of phosphatidylinositol …,5-bisphosphate (PIP2) and its slow resynthesis keeping canonical transient receptor potential channels opened and 2) a mechanism whereby nitric oxide … PIP2 resynthesis and GnRH neuron … from kisspeptin activation.”
Nitric oxide resets kisspeptin-excited GnRH neurons via PIP2 replenishment“Thus, PIP2 in the presynaptic terminal appears to be regulated by postsynaptic activity via a retrograde action of NO.”
“Salt stress increased the abundance of these isoforms, whereas, NO application resulted in decreased accumulation of PIP2 and TIP1.”
Regulation of salt-stressed sunflower (Helianthus annuus) seedling.
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