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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitric Oxide
supplement:
Idebenone
Research Papers that Mention the Interaction
“Consistent with its reported antioxidant function, idebenone significantly reduced the colonic levels of malondialdehyde (MDA) and nitric oxide (NO), and increased the expression of the redox factor NAD(P)H (nicotinamide adenine dinucleotide phosphate) dehydrogenase quinone-1 (NQO-1) in DSS-exposed mice.”
Idebenone Protects against Acute Murine Colitis via Antioxidant and Anti-Inflammatory Mechanisms“These results suggest that idebenone may stimulate the production of nitric oxide , probably through its direct action on nitric oxide synthase, thus producing its protective action on neurological disorders due to cerebral hypoxia or ischemia as a consequence of dilating the cerebral blood vessels.”
Biochemical and histochemical studies of the effects of cerebral metabolism-improving drugs on NADPH diaphorase activity in mouse brain.
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