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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Nitric Oxide and Grape

supplement:

Grape

Research Papers that Mention the Interaction

GE increased nitric oxide ( NO ) production by activating the phosphatidylinositol 3-kinase (PI3K)/Akt pathway in cultured endothelial cells and induced vasorelaxation in the aorta and mesenteric artery via the same pathway.
Biological & pharmaceutical bulletin  •  2020  |  View Paper
Furthermore, GE significantly restored decreases in the renal nitric oxide metabolite content due to ischemia in wild-type mice, but not in eNOS-/- mice.
Biological & pharmaceutical bulletin  •  2019  |  View Paper