“Increasing GRE concentration (1-100 microg/mL) reduced (P <.05) NO production by cartilage tissue explants, and a similar pattern was observed in the production of PGE(2).”
“The inhibitory effects of GRE on NO and PGE(2) production by sow osteoarthrotic cartilage explants observed in this study suggest an important role for GRE as an anti-arthritic agent in osteoarthrosis in the sow.”