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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Nitric Oxide and Diallyl Trisulfide

Research Papers that Mention the Interaction

Recent studies have indicated that some of these sulfur compounds, such as diallyl trisulfide (DATS), alter the levels of gaseous signalling molecules including nitric oxide (NO), hydrogen sulfide (H2S), and perhaps carbon monoxide (CO) in mammalian tissues.
Trends in pharmacological sciences  •  2018  |  View Paper
In a wide range of concentrations (1-100 micrograms/ml), DATS can inhibit the production of NO by macrophages (P < 0.05, P < 0.01).
Journal of Tongji Medical University = Tong ji yi ke da xue xue bao  •  1994  |  View Paper
In addition, DATS inhibited the production of serum nitric oxide NO and myeloperoxidase (MPO) in the lungs of Kunming mice.
International immunopharmacology  •  2015  |  View Paper
DATS activated eNOS (P < 0.05) and increased NO metabolites (P < 0.05).
American journal of physiology. Heart and circulatory physiology  •  2012  |  View Paper
Results DATS significantly inhibited the LPS-induced secretion of NO and PGE2, which was associated with the suppression of their regulatory genes, inducible NO synthase and COX-2.
Journal of cancer prevention  •  2018  |  View Paper