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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Nitric Oxide
supplement:
Cobaltous Cation
Research Papers that Mention the Interaction
“The binding of NO to the Co2+ -enzyme markedly stimulated the cGMP production by forming the five-coordinate NO complex.”
EPR Characterization of Axial Bond in Metal Center of Native and Cobalt-substituted Guanylate Cyclase*“ NO release was also suppressed by 1,2-bis (o-aminophenoxy) ethane-N,N,N',N'-tetraacetic acid (BAPTA), which lowers the intracellular Ca2+ concentration, and was completely inhibited by Co2+ , but it was not affected by verapamil, a voltage-dependent Ca2+ channel blocker.”
“Finally, this work confirms the critical dependence of Co(II) activation ability towards NO upon the center donor properties, reinforced by ligation of strong donor ammonia ligands.”
The dependence on ammonia pretreatment of N−O activation by Co(II) sites in zeolites: a DFT and ab initio molecular dynamics study“An isotropic EPR signal at g = 4.3 suggested a weakly spin-coupled system between cobaltous spin (S = 1/2 or 3/2) and nitric oxide spin (S = 1/2).”
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