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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitric Oxide
supplement:
Black nightshade
Research Papers that Mention the Interaction
“Results in this experiment showed that SNL glycoprotein inhibits 12-O-Tetra decanoylphorbol-13-acetate (TPA; 100 nM)-induced DNA-binding activities of NF-kappaB and AP-1, and enhances NO production in MCF-7 cells.”
Glycoprotein isolated from Solanum nigrum L. inhibits the DNA-binding activities of NF-kappaB and AP-1, and increases the production of nitric oxide in TPA-stimulated MCF-7 cells.“Furthermore, Solanum nigrum increased activation of NF-κB. These findings suggest that Solanum nigrum increases the production of NO by rIFN-&ggr;-primed macrophages and NF-κB plays a critical role in mediating these effects.”
“In this study using mouse peritoneal macrophages, we have examined the mechanism by which Solanum nigrum regulates NO production.”
Solanum nigrum produces nitric oxide via nuclear factor-&kgr;B activation in mouse peritoneal macrophages“SO, IH, and Solanum nigrum (SN) extracts inhibited the nitric oxide ( NO ) production in a dose-dependent manner.”
In Vitro and Randomized, Double‐Blind, Placebo‐Controlled Trial to Determine the Efficacy and Safety of Nine Antiacne Medicinal Plants“Zn-induced NO production promoted an increase in reactive oxygen species accumulation in Solanum nigrum roots by modulating the expression and activity of antioxidative enzymes.”
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