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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitric Oxide
supplement:
Biochanin A
Research Papers that Mention the Interaction
“The results showed that biochanin A suppressed LPS-induced inflammatory mediators nitric oxide , prostaglandin E2 and inflammatory cytokines TNF-α and IL-1β production.”
Biochanin A Inhibits Lipopolysaccharide-Induced Inflammatory Cytokines and Mediators Production in BV2 Microglia“Moreover, biochanin A also significantly inhibited LPS-induced activation of microglia and production of tumor necrosis factor-alpha, nitric oxide and superoxide in mesencephalic neuron-glia cultures and microglia-enriched cultures.”
“ Biochanin A (1-10 microM) decreased the 0.2 mM H2O2-induced production of TNF-alpha, IL-6 and NO in osteoblasts.”
“In NO formation, biochanin A showed marked inhibition, by 62% (50 microM), followed by genistein, daidzein, formononetin, and daidzin, 56, 39, 33, and 8%, respectively.”
“Isotachioside, 4-allyl-2-hydrophenyl 1-O-β-D-apiosyl-(1 → …)-β-D-glucopyranoside, genistein 5-O-β-D-glucoside, and prunetinoside showed a slight … to lower the NO production against LPS-activated microglia with IC50 values of 23.9, 25.3, 28.8, and 34.0 μM, respectively.”
Phenolic constituents from the twigs of Betula schmidtii collected in Goesan, Korea.“In addition, an endothelium-derived activation of voltage-dependent K+ channels contributes, at least in part, to the relaxant effect of biochanin A in renovascular hypertension.”
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