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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Nitric Oxide and Bergenin

supplement:

Bergenin

Research Papers that Mention the Interaction

Bergenin reduced both nitric oxide (NO) production in vitro and malondialdehyde (MDA)/nitrite amounts in vivo.
International journal of molecular sciences  •  2020  |  View Paper
Bergenin treatment was initiated after LPS stimulation for 24 h. The results indicated that bergenin attenuated inflammatory cell infiltration and decreased the concentration of NO , TNF-α, IL-1β, and IL-6, which were increased in LPS-induced mouse mastitis.
In conclusion, bergenin reduced the expression of NO , TNF-α, IL-1β, and IL-6 proinflammatory cytokines by inhibiting the activation of the NF-κB and MAPKs signaling pathways, and it may represent a novel treatment strategy for mastitis.
Inflammation  •  2014  |  View Paper