Possible Interaction: Nitric Oxide and Beets

“ Beetroot juice (BRJ) increases nitric oxide bioavailability and may improve renal blood flow.”

“For example, chronic supplementation of inorganic nitrate in the form of beetroot juice increases circulating NO bioavailability via the nitrate-nitrite-nitric oxide pathway, and has been show to attenuate carotid chemoreflex sensitivity (Bock et al. 2018).”

“ Beetroot juice increases levels of nitric oxide (NO), which serves multiple functions related to increased blood flow, gas exchange, mitochondrial biogenesis and efficiency, and strengthening of muscle contraction.”

“We tested whether consumption of beetroot juice (a rich source of NO3-) for 1 week would increase nitric oxide bioavailability via the nonenzymatic pathway and enhance (1) exercise capacity during an incremental exercise test, (2) physical capability, and (3) free-living physical activity.”

“Plasma NOx was elevated above baseline for 8 h after consuming BTJ and 5 h after BF (P < 0.05).ConclusionsThese data reveal that BTJ and BF are rich in phytonutrients and may provide a useful means of increasing plasma NOx bioavailability.”

“INTRODUCTION Increasing nitric oxide bioavailability via supplementation with nitrate-rich beetroot juice ( BR ) has been shown to attenuate the negative effect of hypoxia on peripheral oxygen saturation and exercise tolerance.”

“The beetroot juice treatment increased plasma NO concentration and decreased oxygen consumption, SBP, and the heart rate-SBP product at rest and at 40%, 60%, and 80% of peak oxygen consumption in the absence of significant effects on RQ, minute ventilation, heart rate, and DBP.”

“These findings suggest that, in healthy subjects, beetroot juice treatments increase plasma NO concentration and decrease cardiac afterload and myocardial oxygen demand at rest and during 3 submaximal levels of aerobic exercise.”

“ Nitrate-rich beetroot juice (BJ) has been shown to acutely increase NO availability and vascular function in healthy and individuals at high risk for CVD .”

“●Acute supplementation with nitrate-rich beetroot juice (BJ) has been shown to acutely increases NO bioavailability ●We showed for the first time that BJ acutely improve endothelial function in HIV-infected patients.”

“Two hours after ingestion the BJ treatment increased [ NO ] and decreased SBP.”

“BackgroundBetaine, beetroot juice , and supplemental nitrate have recently been reported to improve certain aspects of exercise performance, which may be mechanistically linked to increased nitric oxide.”