supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Nitric Oxide
supplement:
Arctigenin
Research Papers that Mention the Interaction
“ Arctigenin suppressed the overproduction of NO through down-regulation of iNOS expression and iNOS enzymatic activity in LPS-stimulated macrophage.”
“Griess assay was used to evaluate the inhibitory effect of arctigenin on the overproduction of nitric oxide (NO).”
In vitro anti-inflammatory effects of arctigenin, a lignan from Arctium lappa L., through inhibition on iNOS pathway.“Additionally, exogenous NO prevented the suppression of STAT3 phosphorylation and survivin expression by arctigenin.”
“Moreover, AG suppressed T. gondii-induced inducible nitric oxide synthase production.”
Arctigenin exhibits hepatoprotective activity in Toxoplasma gondii-infected host through HMGB1/TLR4/NF-κB pathway.“Furthermore, arctigenin increased the NO production by enhancing the phosphorylation of Akt and eNOS (Ser 1177), and inhibiting the expression of NADPH oxidase in thoracic aorta of SHRs.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback