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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitric Oxide
supplement:
Arachidonate
Research Papers that Mention the Interaction
“The effect of nitric oxide on the cell-free NADPH oxidase superoxide-generating system was also examined: The addition of NO before arachidonate activation (t = -6 min) significantly inhibited superoxide anion production.”
Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase.“Using a bioassay preparation in which one cranial window served as the donor for endothelium-derived relaxing factor (EDRF) while the other window was used to assay EDRF, we found that arachidonate applied to the donor window inhibited the generation and/or release of EDRF.”
Inhibition by arachidonate of cerebral arteriolar dilation from acetylcholine.
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