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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitric Oxide
supplement:
Allicin
Research Papers that Mention the Interaction
“ Allicin inhibited interleukin-1β (IL-1β) induced overproduction of nitric oxide , inducible nitric oxide synthase, prostaglandin E2, and cyclooxygenase-2, as well as pro-inflammatory cytokines tumor necrosis factor alpha and interleukin-6 in chondrocytes in a dose-dependent manner.”
Downregulating PI3K/Akt/NF-κB signaling with allicin for ameliorating the progression of osteoarthritis: in vitro and vivo studies.“Inhibitors of nitric oxide NO ) and prostaglandin (PGI2) pathways separately suppressed the vasorelaxation induced by allicin to a certain degree.”
Antihypertensive effects of allicin on spontaneously hypertensive rats via vasorelaxation and hydrogen sulfide mechanisms.“Our data indicate that allicin inhibits lipid peroxidation induced by hyperhomocysteinemia and regulates the excretion and equilibrium of ET and NO , and suggest that allicin might be useful in the prevention of endothelial dysfunction caused by hyperhomocysteinemia.”
“ Allicin treatment showed reduced production of pro-inflammatory cytokines and NO and increased HO-1 activity.”
“Results showed that allicin treatment enhanced the production of pro-inflammatory mediators such as IFN-γ, TNF, IL-12p70 and NO.”
“Both single and combined therapy of fenofibrate and allicin significantly enhanced the levels of NO (P < 0.01 or P < 0.05), but the combined therapy had greatest high EDVR responses (P < 0.01).”
“ Allicin also increased the activity of SOD and NO release and decreased MDA levels.”
Effect of Allicin against Ischemia/Hypoxia-Induced H9c2 Myoblast Apoptosis via eNOS/NO Pathway-Mediated Antioxidant Activity
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