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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nitrendipine
supplement:
Quinidine
Research Papers that Mention the Interaction
“The poteny of nitrendipine was enhanced by several amphiphilic agents by one order of magnitude or more (by pretreatment with quinidine or bepridil).”
Potentiation of cardiodepressive action among calcium antagonists from different classes: evidence for a mechanism at the single calcium channel level“Furthermore, quinidine inhibits rather than stimulates binding of tritiated nitrendipine , nimodipine or (S)-isradipine to isolated cardiac membranes.”
“The negative inotropic potency of nitrendipine is clearly enhanced by quinidine (3·10−6-10−4 mol/l) by up to two orders of magnitude, i.e. cardiac nitrendipine effects are potentiated.”
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