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“significantly potentiated the antinociceptive effect of GTE in both LPS‐induced thermal and behavioural hyperalgesia with nimesulide showing a more pronounced enhancing effect.”
“Rofecoxib (2 mg/kg) and nimesulide (2 mg/kg), COX‐2 inhibitors, also reversed the LPS‐induced immobility, which was significantly potentiated by concomitant administration of GTE.”