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Possible Interaction: Niflumic Acid and Taurine



Research Papers that Mention the Interaction

Topically applied anion channel blockers 4,4′-diisothiocyanatostilbene-2,2′-disulfonic acid (1 mM); 4-acetamido-…,2-disulfonic acid (2 mM); 5-nitro-2-(3-phenylpropylamino) benzoic acid (350 μM); niflumic acid (500 μM); tamoxifen (20 μM) and arachidonic acid (…) all significantly reduced the hyposmotically-induced release of taurine.
Neurochemical Research  •  2004  |  View Paper
Inhibition of taurine release by 5-nitro-2-(3-phenylpropylamino)benzoic acid, niflumic acid , and 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid suggests the involvement of volume-sensitive anion channels.
The Journal of Neuroscience  •  2001  |  View Paper
The osmodependent release of taurine was blocked by a variety of Cl(-) channel inhibitors with the order of potency: NPPB> niflumic acid >DPC>DIDS>ATP.
British journal of pharmacology  •  2000  |  View Paper
Antagonists of the Cl-/HCO3 exchange system, SITS, DIDS and niflumic acid , significantly reduced taurine release.
Neurochemistry International  •  1999  |  View Paper
Both taurine uptake and efflux were inhibited by band 3 inhibitors 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS), 4,4'-dinitrostilbene-2,2'-disulfonic acid (DNDS), niflumic acid , or furosemide.
The American journal of physiology  •  1997  |  View Paper
Thus, NPPB (5-nitro-2-(3phenylpropy1amino)benzoic acid), DIOA (R(+)-[(2-n-butyl4,7dichloro-…-2,3dihydro-1-oxo-l H-inden-5-yl),oxy]acetic acid), niflumic acid and DIDS (4,4'…,2'disulphonic acid) inhibited taurine efflux with the order of potency … 2 DlOA > niflumic acid 2 DIDS.
Biochemical Society transactions  •  1995  |  View Paper