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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Nifedipine and Digitalis

supplement:

Digitalis

Research Papers that Mention the Interaction

Both forms of OAP were shown to be Ca2+-…, as both were prevented by 10(-7) M nifedipine , but only the short OAP were abolished by nifedipine once they had appeared, while high (… mM = 10 times normal) Mg2+ both prevented and terminated short and long OAP in digitoxic preparations.
Magnesium  •  1984  |  View Paper
It is concluded that nifedipine prevents and, in a minor proportion, protects from the toxic effects of digitalis.
Results showed that pre-treatment with nifedipine inhibited digitalis arrhythmias in 10 out of 19 cats and prevented death in the majority of cases (16 out of 19).
Arzneimittel-Forschung  •  1984  |  View Paper