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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Nicotine
supplement:
Tubocurarine
Research Papers that Mention the Interaction
“The effect of nicotine exposure on surfactant gene expression is apparently mediated by nicotinic acetylcholine receptors because it was blocked by D-tubocurarine.”
Nicotine stimulates branching and expression of SP-A and SP-C mRNAs in embryonic mouse lung culture.“4 Dihydro‐β‐erythroidine (DHBE) and tubocurarine antagonized both ACh and nicotine excitations but not those induced by glutamate or dl‐homocysteic acid.”
“T-REx293 cells expressed the nicotinic acetylcholine receptor (nAchR) and tubocurarine , an nAChR antagonist, completely blocked the effects of nicotine.”
“The increased cell proliferation and gene upregulation induced by nicotine were inhibited by addition of the nicotinic receptor antagonist d-tubocurarine.”
“Enhancement of MMP-1 expression by nicotine treatment was eliminated by simultaneous treatment with D-tubocurarine.”
“Mecamylamine (10 μM), dihydro‐β‐erythroidine (10 μM) and d‐tubocurarine (30 μM), but not α‐bungarotoxin (α‐BTX, 0.1 μM), attenuated the NIC (100 μM)‐evoked release of [3H]‐NA.”
“In addition, we demonstrate direct cellular effects of nicotine on primary human bone cells and blockage of these effects with a nicotinic receptor antagonist, D-tubocurarine.”
“The facilitatory effect of nicotine was prevented by 30 µM (+)-tubocurarine.”
“The increase in tau immunoreactivity induced by nicotine , epibatidine, and tacrine, but not the up‐regulation of nAChRs, was prevented by the antagonists d‐tubocurarine and mecamylamine.”
“The effect of nicotine on up-regulation of alpha7 AChRs was partially blocked by either d-tubocurarine or mecamylamine.”
“The effect of nicotine treatment on the number of alpha3 AChRs was only slightly blocked by the antagonists d-tubocurarine , mecamylamine, or dihydro-beta-erythroidine at concentrations that efficiently block alpha3 AChR function.”
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