“In this study, the inhibitory effect of L-theanine , an amino acid derivative of tea, on the rewarding effects of nicotine and its underlying mechanisms of action were studied.”
“We found that L-theanine inhibited the rewarding effects of nicotine in a conditioned place preference (CPP) model of the mouse and reduced the excitatory status induced by nicotine in SH-SY5Y cells to the same extent as the nicotine receptor inhibitor dihydro-beta-erythroidine (DHβE).”