Possible Interaction: Nicotine and Taurine

“Additionally, glutathione and taurine in hippocampus and striatum, phosphocholine in PFC and glycerol in NAc were significantly modified by nicotine , implying the dysregulation of anti-oxidative stress response and membrane metabolism.”

“Human chorionic gonadotropin or taurine supplementation with nicotine prevented the degeneration of germ cells to some extent, restored spermatogenesis moderately with decreased sperm head abnormalities, and enhanced sperm counts, accompanied with increase in plasma and ITT concentrations, testicular StAR gene expression, and key androgenic enzymes activities.”

“injections of nicotine (0.15-0.3-0.6 mg/kg), significantly increased aspartate, glutamate, arginine, taurine , and alanine microdialysate content in the nucleus accumbens.”

“These data suggest that taurine supplementation effectively counteracts the deleterious effect of chronic nicotine administration on bladder and kidney functions and attenuates oxidative damage possibly by its antioxidant effects.”

“At a 5 mM concentration, nicotine produced a more than 200% increase in the levels of aspartate, glutamate and taurine in the striatum; levels of glycine and threonine were also increased.”