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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Coadministration of nicotine and selenium reduced the concentration of lipid peroxidation products and increased the activity of antioxidant enzymes compared to the nicotine group.”
“ Selenium also enhanced the metabolism of nicotine.”
Effects of Exogenous Selenium on Nicotine-Induced Oxidative Stress in Rats“Coadministration of selenium along with nicotine reduced the levels of lipids compared to nicotine group.”
“ Nicotine intake also reduced the absorption of selenium in the intestine.”
“Analysis of plasma revealed reduced quantity of cotinine in the group co-administered with nicotine along with selenium in comparison with the nicotine group.”
“This indicates altered metabolism of nicotine when administered along with selenium.”
“Larger doses of nicotine (10(-2) and 10(-1) M) significantly (P < 0.05) prolonged the recovery of righting reflexes (to 371 +/- 55 and 362 +/- 67 sec, respectively, mean +/- SE ), compared with injection of saline (187 +/- 19 sec).”
“C or Se supplementation with nicotine caused a significant decrease in these concentrations.”
Role of vitamin C and selenium in attenuation of nicotine induced oxidative stress, P53 and Bcl2 expression in adult rat spleen.
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